this post was submitted on 24 Aug 2024
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Initially, THC boosted brain metabolism and synaptic protein levels, indicative of heightened cognitive processes. Subsequently, it shifted towards reducing metabolic activities in the body akin to the effects seen with caloric restriction or intensive exercise, known for their anti-aging benefits.

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[–] [email protected] 103 points 3 months ago* (last edited 3 months ago) (5 children)

The publication itself, which seems to be legit, and well done.

Haven't had a chance to read all of it, but it isn't badly executed by a quick scan.

Edit: I've had a chance to read it in full.

About half of it is over my head. Just don't have the biochemical background to be able to interpret much of the metabolites they were measuring.

That being said, that stuff isn't actually important for casual interest.

Here's the key points I found:

First, the study was mice only. While mice are excellent for this kind of work, you can't guarantee things will be a 1:1 result in Holland p.

Second, the study was for low dose levels, and only delta-9 thc, with no other cannabinoids being used at all.

Third, the study was relatively short, with 42 days being the longer end.

Fourth, and this is the cool part, changes in the relevant metabolites and brain samples had benefit at the 14 day mark. So, if this does translate to human effects, short term, low dose use of delta-9 may be a valuable option. That's years away before this could be confirmed as valid for humans, but the effects were significant.

All of that means that just smoking weed, you aren't going to duplicate the conditions of the study. If you're taking in enough to get high, you're at a higher dose than the study, and that may cause an opposite effect long term.

This is a very focused experiment, with well defined limits and goals. The information gained can not be used as an indicator that smoking herb as an adult human will give any benefit, much less what is in the title of the article.

Think of this study as step one in maybe ten steps you get to the point where it would be useful for indicating benefits in humans, assuming everything went right along the way.

[–] [email protected] 26 points 3 months ago (1 children)

I am glad you linked that, because the article and site itself did not inspire confidence

[–] Angry_Autist 2 points 3 months ago (1 children)

Why wouldn't you look for the study itself in ANY article like this? It's literally linked 1/3 of the way down the actual article.

[–] [email protected] 4 points 3 months ago (6 children)

The very opening basically repeating the name of the college twice and the stocks at the top had me immediately back out of the article as it came across as effectively trash. I then looked at the comments here and was surprised there was an actual publication linked

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[–] [email protected] 65 points 3 months ago (12 children)

I like hearing this so it must be true

[–] Lost_My_Mind 5 points 3 months ago

Found the basis for CNN and Fox News retaining viewership!

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[–] ThePantser 40 points 3 months ago (5 children)

Idk, I'm high right now and my memory is shit.

[–] [email protected] 25 points 3 months ago (1 children)

Younger brains have fewer memories. This checks out.

[–] voracitude 11 points 3 months ago (1 children)

I didn't know you can monkeys paw science

[–] Drunemeton 3 points 3 months ago

The monkey was equally surprised.

[–] [email protected] 7 points 3 months ago (2 children)

Is this why you posted the same comment twice?

Once here

And the other here

[–] ThePantser 7 points 3 months ago (2 children)

What? Maybe your app is broken, those links are the same.

[–] yokonzo 4 points 3 months ago
[–] Sanctus 5 points 3 months ago

Bro is doing PI work on the horny account.

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[–] [email protected] 32 points 3 months ago (1 children)

Same energy as "wine is good for you!" As it turns out, no. Wine is absolutely poisonous to you.

[–] [email protected] 6 points 3 months ago (1 children)

But taking 30 minutes out of your day to relax and unwind? That's good for you.

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[–] sinceasdf 29 points 3 months ago (1 children)

Lmao benzinga the pinnacle of science news

There is a real study it's referencing at least but these fucks are probably just trying to pump weed stocks

[–] [email protected] 4 points 3 months ago
[–] [email protected] 20 points 3 months ago (1 children)

It's amazing to me that they misspelled "reaserch" in the first bullet item.

[–] tyrant 8 points 3 months ago

It's turning back to the time before they knew how to spell

[–] sumguyonline 15 points 3 months ago (1 children)

I've been stoned consistently since covid started. The only "sober" time is when I sleep. I don't think younger, but most things don't bother me. Want to improve your brain? Find consistent ways to reduce stress and perform them daily(like an hour walk outside). That will make you feel and think like a younger you.

[–] [email protected] 3 points 3 months ago (1 children)

You're definitely not sober when you sleep or you'd be talking about the wild ass/sometimes horrific dreams you get when you cut your intake.

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[–] LustyArgonianMana 13 points 3 months ago* (last edited 3 months ago)

No wonder Cheech&Chong, Willie Nelson, Snoop, and Lily Tomlin seem pretty young at heart/mind for their age

[–] ivanafterall 12 points 3 months ago (1 children)

I voted for this because I want it to be true. Yay, science!

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[–] Matriks404 9 points 3 months ago* (last edited 3 months ago)

Well, I don't know if we'll be able to reverse brain aging anytime soon, but we at least know some ways of slowing it down, like by language learning or some other mental tasks.

I personally recommend at least giving a try for learning a new foreign language, it's fascinating journey and even it might be hard at first it's very satisfying in the end. And some people might say that it's not worth it because of AI, but come on, you can still do it for fun, and bigger cultural understanding.

[–] workerONE 7 points 3 months ago* (last edited 3 months ago) (2 children)

When I was 17 I really turned back the clock. Almost every day we were reversing brain aging and boosting mental capacity.

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[–] weariedfae 6 points 3 months ago (3 children)

I wonder if micro dosing can give the same effects? I am a control freak and don't like to be high but worry about cognitive decline. Especially since I got long covid and fucked up my olfactory system. Brain damage sucks.

[–] Angry_Autist 3 points 3 months ago

Most days I microdose by diluting extract in glycerine, roughly 1/4 of a joint paced out thru the day.

Works wonders for my EDS, and I don't feel high at all and have a ton more executive control.

Can't really reply on the cognitive decline but I'm pushing 50 and still in the top .5%

Long Covid did drop me a bit tho, but I guess when you start with a straight eight, losing two cylinders isn't so bad.

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[–] TSG_Asmodeus 4 points 3 months ago
[–] [email protected] 3 points 3 months ago

That's why I'm so smrt

[–] [email protected] 3 points 3 months ago

Another drug that increases metabolism, protein, etc is cocaine. I have hunch these researchers already know what answer they want and are making crappy arguments to confirm themselves

[–] [email protected] 3 points 3 months ago (1 children)

I'm not convinced. Unless the idiot stoners in my area are so fucking stupid that even when you work some science magic to make them smarter, they are still about as intelligent as a sack of dirt.

[–] [email protected] 5 points 3 months ago

Maybe it de-aged their brain too far?

[–] Kintarian 2 points 3 months ago (1 children)

Generally any headline that is that is phrased as a question can be answered with "no".

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