this post was submitted on 29 Sep 2023
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there is a silent threat that affects kitties – chronic kidney disease. It is a complex and irreversible ailment that typically manifests at around 10 years old in cats, affecting an astounding 1 in 3 felines. As cats age, they gradually lose their kidney function, which significantly compromises their quality of life.

Dr. Miyazaki’s breakthrough comes in the form of the “AIM” injection. It’s a medication that has demonstrated an astounding potential to help kitties suffering from chronic kidney disease. The scientist and his team pinpointed the root cause of this treacherous ailment, which paved the way for the development of the injection.

The “AIM” injection is currently in the clinical trial phase and is anticipated to be available by 2025.

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[–] 1bluepixel 121 points 9 months ago (4 children)

The news itself is great, but holy hell is this headline hyperbole. The medicine is a really great treatment and even preventive cure for kidney disease, which is a very common cause of death in old age for cats.

No, this isn't some miraculous treatment that will give all cats a longer lifespan. It's a great cure to a very common cause of death in cats. Not sure where the 30 years figure comes from.

[–] [email protected] 56 points 9 months ago

More info: TikTok

That highly respected journalistic source should give you all the confidence you need in the headline.

[–] Salamendacious 14 points 9 months ago (1 children)

You're 100% right. It isn't a great article but I couldn't find a better one. I just thought people would be interested in reading it. Hopefully better information becomes public soon.

[–] [email protected] 16 points 9 months ago (1 children)
[–] douglasg14b 3 points 9 months ago

That reports on the efficacy of the medicine not necessarily the conclusions drawn from it

[–] [email protected] 6 points 9 months ago

Maybe, I've got an older cat I adopted from a shelter, don't know his exact age. But he's in stage 3 of kidney failure and we've got him on the renal diet. I'm excited to read this news and really hope my boy can stay alive long enough to receive this treatment.

[–] [email protected] 4 points 9 months ago

I've got a kitty with a history of urinary problems so I'm pretty stoked to hear these details.

[–] [email protected] 41 points 9 months ago (1 children)

https://www.nature.com/articles/srep35251

The actual publication, not based off a g-dang TikTok.

[–] [email protected] 2 points 9 months ago

This is 8 years old though, whereas the article is discussing clinical trials.

[–] Wodge 35 points 9 months ago (1 children)

Not to brag or anything, but you see that ultra soft little bad ass of a cat here? He was named Gabriel, or Gaben for short, and he lived to the grand old age of 31. Proper excellent cat.

[–] Salamendacious 7 points 9 months ago

Wow, congrats!

[–] Chickenstalker 31 points 9 months ago* (last edited 9 months ago) (2 children)

The year is 40,000 A.D. Veteran cats deemed too irreplaceable to die will be entombed in a life support sarcophagus deep inside a huge mechanical body, so that even in death they can still serve the Emperor.

[–] [email protected] 9 points 9 months ago

Unexpected 40k

[–] SuddenlyBlowGreen 3 points 9 months ago

You'd want to see a dreadnought on its back, playing with a ball of yarn, don't lie.

[–] CarbonatedPastaSauce 23 points 9 months ago (1 children)

While the "30 years" claim is bullshit, it's great to see work done on this. The paper was released 7 years ago though! My cats are 13 years old and started showing kidney problems over a year ago, but it was caught early and with special diet their numbers are back to normal levels. Get your cats checked with bloodwork, it's relatively cheap! The special diet not so much, it probably tripled my pet food costs, but mine are worth it and I'm sure I've extended their lifespan by years just by catching this early. I will ask my vet about this research on my next visit.

[–] [email protected] 3 points 9 months ago (1 children)

Mine is 19. Nearly lost him a few weeks ago to kidney disease. He's on special diet now and doing better. I can't help feeling like we would have caught it earlier with regular checkups. He's old, deaf, and has an insatiable appetite, I just hope the quality of life he has in his final years are worth it to him.

[–] CarbonatedPastaSauce 2 points 9 months ago

Best of luck! I'm sure he appreciates that you're taking care of him and he's feeling better.

[–] _number8_ 16 points 9 months ago (1 children)

finally, some good fucking news

[–] Salamendacious 6 points 9 months ago

Right? It feels like that sometimes

[–] Pregnenolone 14 points 9 months ago (1 children)

Almost all medical journalism is hot garbage, but Jesus Christ this is something else

[–] [email protected] 10 points 9 months ago

I went looking for better information and I found the initial study published in Nature in 2016 and based on Japanese news sources it does look like the "vaccination" delivery is going into clinical trials soon. The study was quite interesting and the proposed mechanism of action makes sense and was tested both in vitro and in vivo. Here's the link to the 2016 article. (It's kind of dense on the renal physiology and immunology side of things, but the science is sound and potentially can be extended to treat humans with kidney disease in the future.)

https://www.nature.com/articles/srep35251

[–] [email protected] 10 points 9 months ago

Many cat owners would agree, hahaha

[–] [email protected] 8 points 9 months ago

Ok, find a way to prolong my dog's life to about 50 years now, kthx!

[–] Yokozuna 7 points 9 months ago* (last edited 9 months ago) (1 children)

My first cat died from kidney failure. She was about 15 or 16 at the time so she wasnt exactly young. But it really affected me as a kid because I grew up with her. So glad this to read this.

[–] dragonflyteaparty 6 points 9 months ago

Mine was 17. He wasn't old either, but it really sad. He was older than I was.

[–] garretble 6 points 9 months ago (1 children)

Sadly, my cat passed last year from kidney issues.

But maybe this can be a thing for my next cat (whenever that is).

[–] Salamendacious 4 points 9 months ago

I have an 18yo with kidney issues. If this is accurate I'll be talking to my vet soon. Well within the next couple years.

[–] [email protected] 5 points 9 months ago

Great, fix humans next!

[–] Fredselfish 4 points 9 months ago

This awesome!

[–] [email protected] 4 points 9 months ago (1 children)

Is there any info on this from a credible source? The article reads like low-quality clickbait.

[–] [email protected] 2 points 9 months ago

Here's the 2016 study that started things. There are some more recent news articles in Japan from the past couple of years about the project getting funding and going into clinical trials in 2022 or 2023.

https://www.nature.com/articles/srep35251