this post was submitted on 18 Jan 2024
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While it is well known that cannabis can cause the munchies, researchers have now revealed a mechanism in the brain that promotes appetite in a set of animal studies at Washington State University.

The discovery, detailed in the journal Scientific Reports, could pave the way for refined therapeutics to treat appetite disorders faced by cancer patients as well as anorexia and potentially obesity.

After exposing mice to vaporized cannabis sativa, researchers used calcium imaging technology, which is similar to a brain MRI, to determine how their brain cells responded. They observed that cannabis activated a set of cells in the hypothalamus when the rodents anticipated and consumed palatable food that were not activated in unexposed mice.

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[–] [email protected] 31 points 10 months ago

A childhood friend of mine suffers from severe anorexia and was prescribed medical Marijuana for it. It did miracles for her. These types of medical discoveries can and will help many people. Let's keep studying it, and ideally fully legalize weed in the meantime.

[–] [email protected] 13 points 10 months ago (4 children)

How’s this work with those of us who eat less when stoned?

[–] [email protected] 5 points 10 months ago (1 children)

Did you consider emotional issues that are less present when high and otherwise drive you to eat when sober?

[–] [email protected] 3 points 10 months ago (1 children)

It's possible, but I feel like I eat smaller than average amounts when sober anyway.

[–] TIMMAY 5 points 10 months ago

You are demon spawn and will be cleansed by the holy light of eternal munchies

[–] [email protected] 4 points 10 months ago

I thought I was the only one! People always look at me weird because when I'm hungry I smoke a bit and the hunger is gone for a while!

[–] tpyoman 3 points 10 months ago (2 children)

Fuck you dude, I keep getting fat and there's you.....

[–] [email protected] 7 points 10 months ago (1 children)

Sorry mate, have you tried smoking meth?

[–] [email protected] 1 points 10 months ago (1 children)

I used to fall asleep when I did meth a few times, never got the revved up manic shit everyone else did.

[–] [email protected] 4 points 10 months ago

I just stayed up all night and connected with/made the best friend in the world as we talked all night. No fucking idea who he was and never saw him again, 10/10.

[–] WeeSheep 2 points 10 months ago* (last edited 10 months ago)

Ah, you misunderstand, I eat nearly constantly when I'm sober/not high. When I'm high I'm finally ok without eating constantly. I'm already fat.

[–] [email protected] 6 points 10 months ago (1 children)

Been using cannabis daily for several years now and I've always disagreed with the claim that weed causes the munchies. Rather, I would argue that weed blocks communication between the stomach and the brain. Essentially, if you start eating, it is easier to keep eating because the message that your stomach is getting full gets lost ("the munchies"). However, if you are hungry right before you smoke, the urge to eat goes away after smoking (or at least becomes a lot easier to ignore). I lost a lot of weight thanks to weed simply by never eating when I was high.

This is all anecdotal of course, but every daily smoker I've talked to agrees with me.

[–] renrenPDX 1 points 10 months ago

Same for me. I also smoke daily when I water fast and have no issues not eating for extended durations. If anything, I find it helps avoid eating.

[–] DarkShaggy 2 points 10 months ago (3 children)

And in other news water is wet!!!

[–] heydo 13 points 10 months ago (3 children)
[–] Plopp 4 points 10 months ago

It probably pissed itself.

[–] [email protected] 3 points 10 months ago
[–] [email protected] 1 points 10 months ago

It's the essence of moisture

[–] [email protected] 6 points 10 months ago* (last edited 10 months ago)

Did you not even read past the headline?

[–] JeffreyOrange 5 points 10 months ago

And in other news you can't read.

[–] DerpDerpingtonIsHere 1 points 10 months ago

You don't say.

[–] [email protected] -5 points 10 months ago (1 children)

Wooooooow such a… discovery…

[–] [email protected] 3 points 10 months ago (1 children)

Had studies like this already found the same mechanisms?

[–] [email protected] -3 points 10 months ago (1 children)
[–] [email protected] 3 points 10 months ago (1 children)

Yes. That's what science is about...lol

[–] [email protected] 0 points 10 months ago (1 children)

Wow I’m not a scientist, and I know this 30 years ago … and I’m not the only one…

[–] [email protected] 1 points 10 months ago

Some people also "know" that going outside with cold hair causes people to catch a cold, but that's not true.

In addition, studies help determine to what extent and effect happens. Studies also help determine what and where any edge cases might be, which can be important for treating illnesses, for example.