this post was submitted on 31 Dec 2023
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A Welsh scientist working on a new male pill wants to reduce the burden on women of protecting against unwanted pregnancies.

Prof Chris Barratt is leading research on a non-hormonal drug which prevents sperm cells from reaching an egg.

His team at the University of Dundee has received significant funding from the Bill and Melina Gates Foundation.

"It's been a very poorly researched topic for 40 or 50 years," Prof Barratt said, but society has changed.

His team's research could see men given a gel or a pill that would affect the sperm cell, effectively disabling its function.

Instead of targeting the production of sperm, his research focuses on slowing the sperm cells' swimming action down and making them similar to those in infertile patients.

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[–] [email protected] 33 points 11 months ago (4 children)
[–] [email protected] 20 points 11 months ago (3 children)

Adding to this: as a mid-20s person, I was always told that I would not be able to get a vasectomy without certain stipulations, like already having children. That really pisses me off, since that defeats the entire point.

I recently talked to my doctor though, and they stated that that is not the case(for men, women evidently don't get to control their bodies). So for anyone else trying to get one, make sure to talk to your doctor. They may be able to hook you up.

[–] [email protected] 5 points 11 months ago

Yeah I got mine no problem, but I found the urologist on the r/childfree wiki's list of doctors. Fuck reddit, but it is a good resource, and they have doctors for vasectomies and hysterectomies

[–] [email protected] 2 points 11 months ago (1 children)

I think this is one of those things that depends where you are. I've heard of guys trying to get vasectomies in the deep south getting the run around because they didn't have kids.

[–] CADmonkey 1 points 11 months ago

This is what I experienced in Oklahoma.

[–] CADmonkey 5 points 11 months ago (1 children)

Almost a year since I had mine done, my wife and I both enjoy it.

[–] [email protected] 3 points 11 months ago
[–] [email protected] 4 points 11 months ago

It wasn’t that bad. And I’m glad I did it. No more kids.

[–] [email protected] 2 points 11 months ago* (last edited 11 months ago) (2 children)

Isn't there a risk from ball pain?

Like forever not for healing.

[–] [email protected] 2 points 11 months ago (1 children)

I think there is a slight risk of that, not sure. Not something to cheap out on, go for the best doctor you can

[–] [email protected] 3 points 11 months ago (1 children)

I come from a first world country so I don't think I would be paying or choosing a doctor.

[–] [email protected] 1 points 11 months ago
[–] CADmonkey 1 points 11 months ago (1 children)

I was worried about it hurting, and I'll be honest I could have done it over a lunch break at work. Almost zero pain, and my wife watched the surgery, which didn't even last as long as one Metallica song.

[–] [email protected] 2 points 11 months ago (1 children)

What I'm on about is a long term pain.

Something more like blue balls

[–] CADmonkey 1 points 11 months ago

It's been almost a year, and i feel completely normal. Zero pain.

[–] stevedidWHAT 20 points 11 months ago (1 children)

I’ll take the ball bath over fucking with my hormones any day of the week. I saw what they did to women

[–] [email protected] 12 points 11 months ago* (last edited 11 months ago) (2 children)

I saw what they did to women

Part of it is that women are currently using it and taking on all of the risks/consequences from it. Some couples would like the ability to transfer the risk to the other partner (different couples will have different reasons for their choice).

Another thing to note is that regulatory agencies are more strict now than back when there was a focus on birth control for women. Like that thing with alcohol would be banned if it was "invented" today. If a male pill IS approved, it would likely be a lot safer than what women are taking now.

Idk about this specific trial, I'm speaking generally

[–] [email protected] 7 points 11 months ago* (last edited 11 months ago) (1 children)

It's not really that the regulators have become more strict. Most of the female birth control options would likely be approved today. The issue with male birth control is more the way they assess whether a medication is 'worth it' to take.

For women the risk and side effects of birth control are weighted against being pregnant. Since being pregnant is really dangerous, the side effects can be more severe. For example, hormonal bc causes a slight risk of a stroke, however being pregnant causes this risk to go up more. Therefore the risk of the bc is acceptable.

For men there is no such medical benefit to bc, therefore it must have very very little to no side effects to be approved.

[–] stepan 1 points 11 months ago

So it has to do with threshold and relative risk/loss analysis?

[–] stevedidWHAT 3 points 11 months ago

I share sentiments with tessellecta - not so sure we looked at all the features when comparing apples to oranges

[–] [email protected] 11 points 11 months ago (1 children)

I'm not sure if this is the same one I read about before (YCT529) the article doesn't seem to mention it be name. If it is I would be very wary of side effects, being a retinoic acid receptor antagonist it's basically doing the opposite of tretinoin.

[–] MicroWave 10 points 11 months ago

Looks like this one is not YCT-529, which is being developed by YourChoice and the University of Minnesota College of Pharmacy.

https://www.pharmacy.umn.edu/news/yourchoice-therapeutics-begins-first-human-trial-male-birth-control-pill