Not sure, but I think I know what you're talking about... Have you checked SuperSlicer? I'm not saying they have a solution - hadn't used it in years and just checked it out again recently. It's a fork of PrusaSlicer that has a lot of advanced and niche tweaks. Just one example I noticed when I downloaded it recently: do you know about the floating hole issue for bolt inserts, where slicers just make bridged circles floating in air, and you have to do some hack with one layer thick square cutouts in the model to fix that? SuperSlicer has a built in option for it that just already slices that correctly - saw it in their release notes and tried it, worked great.
That is all to say, they have a lot of advanced tweaks for slicing issues, in the familiar package of Slic3r and PrusaSlicer UI, so might be worth checking it out