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I am a researcher studying diseases. You have no idea how many mice get killed without generating any data. There's a rule in place whenever you want to work with animals that you need to plan ahead and only use as few animals as you need to get the data that you're looking for. But things in research basically never happen according to plan. It could be due to a variety of factors: unexpected failures, overlooked factors, technical errors, or just simple negligence when performing an experiment. A lot of data and samples obtained from killed mice are discarded for one or more of the above reasons.
I get that mouse experiments are important to prove that our findings can translate to actual living animals, but I personally will not touch a mouse because, frankly, the "useful data per mouse" ratio is way too low for me to justify using mice.
Imagine if we were doing this to our own species.
We did during WW2 and that pushed medicine further in just a few years than thousands of years of medical history before that.
Yeah, I don't think it was consensual