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I'm trans in the US. After insurance I pay about $300 to $400 every 3 months for blood tests and a follow up. My meds cost me an additional $90 for 3 months as well. They are my hormones and another medication unrelated to me being trans. I get my meds at a local independent pharmacy, so they are relatively cheap. I used to get them at a large chain pharmacy and they were about twice as much there.
I also used to work as a cashier at a pharmacy. I once had to ring someone up who was paying over $3,000 for some cancer medication. It also wasn't uncommon to see people paying around $500 for medications that they need to be alive.