Be sure to follow the rule before you head out.
Rule: You must post before you leave.
Brotherhood of Steel - only reason they're alive is that Veronica would be sad
Boomers - Nuke the site from orbit
Khans - the two hippies that give and sell drugs to you are cool, they get to live for now
White Gloves - On probation
Omertas - lol no
Followers of the Apocalypse - Based
NCR - imperialists mfs
You can keep Veronica as your companion if you finish the Brotherhood quest line and then manually kill all members with weapons instead of blowing up the bunker. You lose less rep somehow.