this post was submitted on 10 Dec 2023
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Have you got more details on that? I wouldn't classify it as a hard reset but I never did the crazy high doses.
I'm speaking more personally/anecdotally but it can really shift things around from a high 2nd plateau - 4th on. I haven't done a 4th plateau cuz it scares the fuck out of me but there you have it
Edit: there seems to be a lot of work being done(+ its very in vogue right now/fashionable) to use ketamine to treat depression. Ketamine is also an anaesthetic and NMDA-antagonist at supra-therapeutic doses...