this post was submitted on 25 Dec 2024
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they've made juicero of backyard chemistry. everything you can do with that bullshit jar strapped to arduino you can do with hotplate and standard glassware - and cheaper - and even more because their setup doesn't allow you to run reflux sanely among others. putting procedures as a set of instructions for said arduino is no substitute for actual expertise. iirc their procedure for naloxone can fail in such a way that another pharmaceutical of opposite activity can be made (oxymorphone). there's zero analysis or quality control that would catch this. they're trying to generate synthesis pathways with ai. laufer has no actual training in chemistry, his degree is in maths and i suspect heavy case of engineer syndrome
there's also little consideration, if any, about purification and waste management. do you feel lucky?
that sounds..... questionable, almost at best. i will still probably tune in, but i'm now prepared to be kind of horrified honestly. i'm not sure someone with a math degree and no chemistry experience is the best source for this kind of information, especially when the substances being produced are meant to be consumed.
even with a chemistry degree, it’s very common for professionals to overestimate others ability to comprehend their field, and for beginners to overestimate their ability
when it comes to synthesising drugs, that’s a recipe for disaster
good thing these guys seem in love with automating the process... 🙃
leaving most of the brain-thinkie parts up to an arduino totally solves the "this might kill someone" factor. no-knowledge synthesis is the future! (/s for anyone wanting to toss reagents in a jar, and hope robots are infallable)
really tho, mistakes that make fries taste bad, or twist an ankle don't have shit on barely messing up a step in a synthesis that is to be consumed. it is like their reckless abandon is also intended to be a part of their cause, which makes things more confusing, and raises even more ethical questions.