fermionsnotbosons

joined 1 year ago
 

I assume anyone who comes here will either have completed a reaction or studied one (computationally, in a course, for fun, etc.) recently, so why not share favorites? Include why you liked it best, if you feel like elaborating!

I'll go first.

Mine might be the reaction of an oxime (in dichloromethane) with an O-protected propargylic alcohol, using bleach and triethylamine. The oxime gets converted into a nitrile oxide by the bleach and base, and then undergoes a 3+2 cycloaddition with the alkyne to produce an isoxazole VERY cleanly. Work-up of this biphasic reaction consisted of partitioning the phases and concentrating the organics (after a weak acid wash and silica plug), resulting in publication-quality NMR data without further purification going into the next step! Very good for me as it is a key precursor that needs to be made in very large (for R&D) quantities.

It's not super fancy by any means, but I love cycloadditions, heterocycles, and reactions that are successful with minimal byproducts (don't we all?), lol.

[–] fermionsnotbosons 3 points 1 year ago

I am in full support of this approach. There won't be a one-size fits all solution that works everywhere for every type of lot, but it sounds like the state government is allowing for creativity and flexibility in how developers make this happen. I hope there is still enough oversight to minimize negative environmental outcomes and make sure the people that need it most get housed, but it doesn't has to be done perfectly to have a hugely positive impact on our communities.

[–] fermionsnotbosons 4 points 1 year ago (1 children)

I would have said Party Down but they went ahead and did it. I haven't seen the new episodes yet though...

[–] fermionsnotbosons 5 points 1 year ago

Thank you for doing this, now I can more effectively manage my cat community subscriptions to get the perfect ratio of cat to everything else!

[–] fermionsnotbosons 1 points 1 year ago

Heard on the radio broadcast that scouts were worried about Whitmore's 'basketball iq', possibly from recent workouts? Whatever the fuck that means. Dude can obviously play well enough, has all the tools and talent, and is a steal for the Rockets at 20.

[–] fermionsnotbosons 1 points 1 year ago

True, someone reliable to handle the ball is needed now (to lower Lebron's usage) and in the future -and Hood-Schifino has great potential - but I am just saying they had options with a better chance to be plug and play into the rotation. The front office of the Lakers hopefully has something up their sleeve that gives them a fighting chance to come out of the west in 2024 without completely sacrificing their long-term future, but if they had to err in any direction I wish it was towards winning now.

[–] fermionsnotbosons 1 points 1 year ago

Yes, that was my first thought too seeing Jacquez Jr. at the 18 spot. I thought maybe I was biased because of UCLA affiliation but either way he's seasoned as hell compared to all these one and done players. I feel like Miami picked him for just that reason, and I have no doubt he'll give them valuable minutes during their 2024 playoff run.

[–] fermionsnotbosons 7 points 1 year ago (4 children)

Why does nba.com list J. Hood-Schifino at 6-4 but then in their analysis call him a 'big point guard, standing at 6-foot-6'? Weak. Anyway, I am not sure about the pick considering that the Lakers need to get better ASAP. Seems like a pick for the post-Lebron future, I guess.

[–] fermionsnotbosons 3 points 1 year ago

Gila! Gila!

I heard Gila Monster and Dragon as singles already, of course. I was impressed with both - maybe Dragon wins by a snout for the more interesting (IMO) guitar riffs, and the syncopation between those and the drums/bass is pretty cool. The overall style being less thrash and more prog sounding than Gila Monster makes me favor it a bit more as well. Gila Monster sounds like it could have been made by Ride the Lightning or Master of Puppets era Metallica - if they took themselves a little less seriously - which is very badass too.

I will listen to the album all the way through tonight and report back!

[–] fermionsnotbosons 1 points 1 year ago

I definitely will! I already subscribed to it a day or two ago (still pending, I guess). Thanks for the reminder to visit anyway!

[–] fermionsnotbosons 1 points 1 year ago

I was fascinated with the Aiel when I first read the books, so The Shadow Rising and The Fires of Heaven were 1a and 1b for me. On my last re-read I really liked The Path of Daggers and Winter's Heart the best. On this re-read I am now on WH, and I still love it, but who knows? Maybe this time through Knife of Dreams will leapfrog to the top (it's already up there as it is), and eventually Sanderson's style will click and I'll like one of the final three books best when it's all said and done.

I dunno, I grew up with the books, and as I get older I identify with the story and RJ's style in different ways. He was a master at depicted the subtle nuances of character growth so well, and with his limited 3rd person perspective I find myself in the shoes of each main PoV character and those shoes don't always fit the same, lol.

Just yesterday I read the chapter where Rand first sees the steam engine prototype in action, while debriefing Dobraine at his academy in Cairhein. So much was packed into such a otherwise mellow scene. I love these books so much :)

[–] fermionsnotbosons 5 points 1 year ago

I am pretty sure I saw a homelab community on lemmy.ml already, just FYI.

[–] fermionsnotbosons 3 points 1 year ago

Yeah, the cat posts sprung up fast which made me very happy, lol.

And Hendrix says thanks for the compliment. You'll definitely see him on here again, he's too photogenic not to share.

66
Who dat? (lemmy.world)
submitted 1 year ago by fermionsnotbosons to c/cat
 

Woke him up from nap #6 that day.

 

She hears the crinkling sound of the paper bag and comes running from the other room.

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