Lemmy.World

168,724 readers
7,661 users here now

The World's Internet Frontpage Lemmy.World is a general-purpose Lemmy instance of various topics, for the entire world to use.

Be polite and follow the rules βš– https://legal.lemmy.world/tos

Get started

See the Getting Started Guide

Donations πŸ’—

If you would like to make a donation to support the cost of running this platform, please do so at the following donation URLs.

If you can, please use / switch to Ko-Fi, it has the lowest fees for us

Ko-Fi (Donate)

Bunq (Donate)

Open Collective backers and sponsors

Patreon

Liberapay patrons

GitHub Sponsors

Join the team 😎

Check out our team page to join

Questions / Issues

More Lemmy.World

Follow us for server news 🐘

Mastodon Follow

Chat πŸ—¨

Discord

Matrix

Alternative UIs

Monitoring / Stats 🌐

Service Status πŸ”₯

https://status.lemmy.world

Mozilla HTTP Observatory Grade

Lemmy.World is part of the FediHosting Foundation

founded 1 year ago
ADMINS
1
 
 

cross-posted from: https://lemmy.world/post/11053067

cross-posted from: https://lemmy.world/post/11053065

After assessing the semantic similarity between 15,000 reports linked to the use of 165 psychoactive substances and 625 NDE narratives, we determined that the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine consistently resulted in reports most similar to those associated with NDEs. Ketamine was followed by Salvia divinorum (a plant containing a potent and selective receptor agonist) and a series of serotonergic psychedelics, including the endogenous serotonin 2A receptor agonist N,N-Dimethyltryptamine (DMT). This similarity was driven by semantic concepts related to consciousness of the self and the environment, but also by those associated with the therapeutic, ceremonial and religious aspects of drug use. Our analysis sheds light on the long-standing link between certain drugs and the experience of β€œdyingβ€œ, suggests that ketamine could be used as a safe and reversible experimental model for NDE phenomenology, and supports the speculation that endogenous NMDA antagonists with neuroprotective properties may be released in the proximity of death.

2
 
 

cross-posted from: https://lemmy.world/post/11053065

After assessing the semantic similarity between 15,000 reports linked to the use of 165 psychoactive substances and 625 NDE narratives, we determined that the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine consistently resulted in reports most similar to those associated with NDEs. Ketamine was followed by Salvia divinorum (a plant containing a potent and selective receptor agonist) and a series of serotonergic psychedelics, including the endogenous serotonin 2A receptor agonist N,N-Dimethyltryptamine (DMT). This similarity was driven by semantic concepts related to consciousness of the self and the environment, but also by those associated with the therapeutic, ceremonial and religious aspects of drug use. Our analysis sheds light on the long-standing link between certain drugs and the experience of β€œdyingβ€œ, suggests that ketamine could be used as a safe and reversible experimental model for NDE phenomenology, and supports the speculation that endogenous NMDA antagonists with neuroprotective properties may be released in the proximity of death.

3
 
 

After assessing the semantic similarity between 15,000 reports linked to the use of 165 psychoactive substances and 625 NDE narratives, we determined that the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine consistently resulted in reports most similar to those associated with NDEs. Ketamine was followed by Salvia divinorum (a plant containing a potent and selective receptor agonist) and a series of serotonergic psychedelics, including the endogenous serotonin 2A receptor agonist N,N-Dimethyltryptamine (DMT). This similarity was driven by semantic concepts related to consciousness of the self and the environment, but also by those associated with the therapeutic, ceremonial and religious aspects of drug use. Our analysis sheds light on the long-standing link between certain drugs and the experience of β€œdyingβ€œ, suggests that ketamine could be used as a safe and reversible experimental model for NDE phenomenology, and supports the speculation that endogenous NMDA antagonists with neuroprotective properties may be released in the proximity of death.

view more: next β€Ί