Uiua
This turned out to be reasonably easy in Uiua, though this solution relies on macros which maybe slow it down.
(edit: removing one macro sped it up quite a bit)
(edit2: Letting Uiua build up an n-dimensional array turned out to be the solution, though sadly my mind only works in 3 dimensions. Now runs against the live data in around 0.3 seconds.)
Data β β(β‘βββΈ(Β¬β": "))βΈβ @\n "190: 10 19\n3267: 81 40 27\n83: 17 5\n156: 15 6\n7290: 6 8 6 15\n161011: 16 10 13\n192: 17 8 14\n21037: 9 7 18 13\n292: 11 6 16 20"
Calib! β β‘ββ’β½βΈβ‘β(ββ/[^0]:Β°β) # Calibration targets which can be constructed from their values.
&p/+Calib!β(+|Γ)Data
&p/+Calib!β(+|Γ|+ΓβΏ:10+1ββββ,)Data