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Ritalin vs Concerta dosage (lemmy.ml)

submitted 3 months ago* (last edited 3 months ago) by [email protected] to c/adhd

9 comments fedilink hide all child comments

When I take Ritalin, I need to take an initial dose of 15-20mg for it to be effective (and then taper it down every 50 minutes otherwise I get jittery). But when I was on Concerta, 18mg was not enough, even though it is roughly the same dosage. Is the Concerta dosage not comparable to that of the Ritalin as it is spread out over a longer period? I know 30mg of Ritalin would be way too much for me – but does that necessarily mean that 36mg of Concerta would too?

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[–] [email protected] 12 points 3 months ago (1 children)

My understanding (and it's relatively poor even though I take Concerta myself) is that the mg is the total dosage that will be gradually released from the XR capsule over the day - so for the majority of the day (especially in the morning) you're feeling far less than 18mg of methylphenidate in active use.

I think this is a discussion to have with your doctor but I'd suggest not coming in overly rationalizing - just tell them how you're feeling on the dose (i.e. it's less impactful) and see what they suggest.

Personally, I've found a different efficacy in Concerta vs generic methylphenidate XR at the same dosage and that tracks with my general impression of any neurological pharmaceutical agent... some things randomly work better for some people and violate common expectation or reason because brains are really fucking complicated, everyone is different, everyone has different brain chemistry, ADHD (and all other neurodivergences) are diagnosed by symptom rather than cause, and, most importantly, we really don't have a fucking clue why things are effective and the entire field of neurochemistry is really just vibes based.

I hope you find a good resolution!

[–] [email protected] 2 points 3 months ago

Ah I see, I suspected the dosage labelling might work this way.

[–] [email protected] 3 points 3 months ago (1 children)

If you say Ritalin, you mean the "normal" version without extended release, right? It is individual how many hours Concerta has an effect, but it's roughly 7-10h.

How much mg of Ritalin do you take in 7-10h in total? That is roughly the dosage you need for Concerta.

[–] [email protected] 2 points 3 months ago

Ooh, quite a lot. My Ritalin (yes it is IR) dosage tends to go 15mg - 50min - 10mg - 50min - 5mg - 50min - 5mg. So that does roughly equal the 36mg dose of Concerta I guess

[–] [email protected] 3 points 3 months ago

While you already have your answer, I thought I'd share this for anyone wanting to know a bit more about how Concerta works. The pills themselves use an osmotic-controlled release oral delivery system where part of the dose is given immediately and the rest is slowly given as the drug gets squeezed out a little hole (that's drilled out by lasers!) by osmotic pressure. It's really cool stuff and makes it quite different to Ritalin IR in how it feels and works.

[–] cheese_greater 2 points 3 months ago* (last edited 3 months ago) (3 children)

How do you know its not enough?

[–] [email protected] 4 points 3 months ago

Because they felt that way?

Dosage is very subjective.

[–] [email protected] 3 points 3 months ago

Because it doesn't calm my restless limbs and brain the way 15mg of Ritalin does.

[–] [email protected] 2 points 3 months ago

thats a real problem, took me ages to figure out.