Lemmy.World

Occupational exposure to silica or silicon dioxide dust has been examined as a possible risk factor with respect to several diseases, like tuberculosis, lung cancer, systemic vasculitis , rheumatoid arthritis, systemic sclerosis , systemic lupus erythematosus , renal involvement , etc.

Early in 1951, Saita G et al.firstly reported that the renal functions were decreased in some silicosis patients. Subsequently, several epidemiological evidences suggested that the silica exposure was associated with an increased risk of end-stage renal disease (ESRD), chronic kidney disease (CKD), or specifically glomerulonephritis.

Silica nephropathy referred to the floorboard of kidney diseases after exposure to silica or silicon dioxide, including tubulo-interstitial disease, immune-mediated disease, chronic kidney disease, and end-stage renal disease. In literatures, the renal histopathology of silica nephropathy was varied, including focal glomerureview ritis, necrotizing glomerulonephritis, crescentic glomerulonephritis, etc.

Occupational exposure to silica or silicon dioxide dust has been examined as a possible risk factor with respect to several diseases, like tuberculosis, lung cancer, systemic vasculitis , rheumatoid arthritis, systemic sclerosis , systemic lupus erythematosus , renal involvement , etc.

Early in 1951, Saita G et al.firstly reported that the renal functions were decreased in some silicosis patients. Subsequently, several epidemiological evidences suggested that the silica exposure was associated with an increased risk of end-stage renal disease (ESRD), chronic kidney disease (CKD), or specifically glomerulonephritis.

Silica nephropathy referred to the floorboard of kidney diseases after exposure to silica or silicon dioxide, including tubulo-interstitial disease, immune-mediated disease, chronic kidney disease, and end-stage renal disease. In literatures, the renal histopathology of silica nephropathy was varied, including focal glomerurevieritis, necrotizing glomerulonephritis, crescentic glomerulonephritis, etc.