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In conclusion, with respect to work‐related disease and potential compensation, it is essential to recognize silica exposure as a risk factor for developing AAV such as MPA. Our case emphasizes the importance of primary physicians identifying this relationship in addition to taking a thorough occupational history.

Published in 2017

Herein, we discuss silica exposure and the risk of ANCA‐associated vasculitis (AAV), particularly in terms of work‐related diseases. Silica exposure is a notorious risk factor for developing AAV, which is potentially lethal when not identified.

Microscopic polyangiitis (MPA) is a primary systemic vasculitis commonly known as antineutrophil cytoplasmic antibodies (ANCA)‐associated vasculitis (AAV), characterized by inflammation of small‐sized blood vessels and serum positivity of ANCA.

Patients with MPA typically present with pulmonary, kidney, and neurologic manifestations. Although the definitive pathophysiology of MPA is still not fully understood, certain factors such as drugs, bacteria, and dust exposure are known to trigger the development of this disorder.

Published 2017

Silica exposure is a notorious risk factor for developing AAV, which is potentially lethal when not identified.

When we see a silicosis patient with new‐onset prolonged fever and generalized fatigue, AAV should be taken into consideration. This case report provides beneficial information to reliably assess patients at high risk of developing AAV in primary care settings.