I wore a crappy 10kg weighted vest as often as I could for about two months, hoping that it would turn me into Goku. It was extremely draining, and I felt like I would never get used to it.
And I didn't. Not really. It was difficult to wear for more than one day, and I couldn't really gauge if I had spent enough time recovering from my last session before I put it back on. I'd wear it on and off throughout the day and then go for a run, then take it off for a day or two and put it back on once I felt back to normal. But I'd quickly realize I hadn't fully recovered.
I just never felt like I was getting the most out of it or using it to its full potential. I experimented quite a bit, but it was a lot different than other exercise tools.
I guess my advice would be to take it slow. Slower than you'd think. Especially when you start hiking and running and sweating in it.