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My condolences. I have some people in the family who are furious with my MIL, and I keep having to remind them that it's the disease. I'm probably the most patient with her, but even I struggle to be with her for any length of time without getting angry, even with the knowledge that it's not her.

My step-father is in the advanced stages of Alzheimer's, and he's been on medication from the start, which has been a mixed blessing. He's hung on for longer than usual, but just stays on this side of palliative/hospice. It's sad because he's such a drain on my mother. He's much easier to deal with than my un-diagnosed (and refusing to see any doctors) MIL, but my mom says the hardest thing about my step-father is that he's not the man she married, and it's like living with a complete stranger. It's eerily similar to what my wife says about her mother: she says her mom died years ago, and the woman in her body is a stranger.

Personally, after these experiences, I have warned my entire family, and have an agreement with my wife, that if I start to decline in this way, before it gets that bad we're going to take a visit to Switzerland and I'm going to get in a Sarco Pod. No shade on people who don't want to do this, but I neither want to experience it, nor inflict my symptoms on my loved ones.