thejoker954

Hit and run is NOT the answer to any question involving vehicles.

I feel like this is related to the can't measure the coast' thing.

Like if you zoom in enough you are always traveling in a straight line.

Not necessarily. Japan is 'weird'.

It may be considered proper to be introduced by your parent/elder.

edit Could also be a mistranslation. Perhaps he ment 'sorry for finding out about her death this way.'

I've never thought about it. I always just assumed lichen was just a specific type of moss.

Im required to have health insurance, but health insurance costs me so much I can't actually afford to use it.

And despite struggling to put food on the table every week I make 'too much' to qualify for any assistance.

Not really.

And Tianeptine is an atypical tricyclic anyways.

But to address your question specifically:

Taken from National Library of Medicine - ..."Although TCAs demonstrate equivocal efficacy with SSRIs when treating MDD, these medications cause more significant adverse effects due to their anticholinergic activity and lower threshold for overdose. Due to these factors, TCAs are typically not considered the first-line treatment for MDD, even though they have been proven highly effective in managing severe or treatment-refractory depression"...

And from wikipedia - "Adverse effects have been found to be of a similar level between TCAs and SSRIs"

..."Newer antidepressants are thought to have fewer and less severe side effects and are also thought to be less likely to result in injury or death if used in a suicide attempt, as the doses required for clinical treatment and potentially lethal overdose (see therapeutic index) are far wider in comparison."...

..."They are not considered addictive and are somewhat preferable to the monoamine oxidase inhibitors (MAOIs). The side effects of the TCAs usually come to prominence before the therapeutic benefits against depression and/or anxiety do, and for this reason, they may potentially be somewhat dangerous, as volition can be increased, possibly giving the patient a greater desire to attempt or commit suicide."...

To go back to tianeptine specifically it's basically unregulated here in the USA due to money.

Big Pharma doesn't control the patent for it so it can be made cheaply and in bulk.

Combined with it being a TCA (aka 'old version') FDA and others have no reason to try and fight the corporate overlords to classify it as a legitimate drug (despite its use as such in multiple countries).

This of course put it in the grey market. It's a drug that can make you feel good and you dont need (can't get) a prescription for it. And it can be made cheaply and easily.

Of course people are gonna abuse the situation.
Classifying it as medication and requiring a prescription prevents the abuse.

Seriously you have to take waaay above the recommended dosage regularly to get addicted to Tia.

Most of the abuse/addiction came from people who were already abusing opioids and switched to Tia as a 'better' alternative.

Sprinkle in some dumb kids and shady manufacturers (again regulation would fix this) and boom you got your hot new craze to scare people with.

I totally get what he is saying. Although D&P might not be the best example because it has what a lot of movies nowdays are missing.

Love.

The actors love the characters and each other.

It wasnt just another day in The 'office'. And that reads on screen.

A lot of movies are just soulless right now. If not built by AI then they they are built by committee.

Those side effects arent the 'norm' though. They are a result of long term high dose usage. (Plus gas station quality control)

Using proper dosage (and legit formula not cut with anything else) side effects are potentially no worse than any other drug/ tricyclic antidepressant.

As an aside, I'm pissed about Tia. The sulfate especially worked wonders on my anxiety and depression with no major side effects.

it being in the grey market (due to shitty politics) instead of being recognized like other countries as legitimate medicine leading to it's abuse is a real problem.

Yeah its not charisma you need - it's confidence.

But if you mount it as a foregrip you double your firepower and control.