Gaming: I just Steam for most games, I use Proton GE for better performance in some games
General SW: For things that are light and work with Wine, I will use just that. For SW that needs the Windows "runtime" like the Xbox Accessories SW for my Elite controller, I use a VirtualBox.
Most of my needs are covered by regular Linux apps, such as a Browser, Development environment and Media.
Dude, I run Elden Ring in my desktop and stream it to my deck, no cables and lot's of battery time. eGPU is cool if you use your steam deck as a PC.