andrei_chiffa

joined 1 year ago
[–] andrei_chiffa 3 points 1 year ago (1 children)

@[email protected] seems to have given all the background info :)

[–] andrei_chiffa 6 points 1 year ago

Sure.

The problem is that the brain is not a squishy uniform cell mess that just reacts to some chemicals (dopamine/serotonine/...). All of those are neurotransmitters to specific classes of neurons that have a very specific topological position to perform their function.

So if you just throwing in random neurons here and there, they won't do anything. They are not contributing to any pathways.

Serotonin re-uptake inhibitors and dopamine generator drugs (aka opioids) make the signal send by the "correct" neurons that are there stronger, contributing to the desired effect.

The problem with Alzheimers is the death of "correct" neurons, that occurs before Alzheimer is manifested. So just injecting new ones is unlikely to do anything.

Moreover, the neurons don't just live outside brain. They need to be immortalized to live in a Petri dish. And to acheive it, the only way we can go now is to add factors that in the context of human organism are considered as cancerous.

So it's a combo of "unlikely to be efficient" and "potentially likely to lead to cancer". With Parkinson the tradeoff might be acceptable, but this kind of projects is definitely that raises some red flags for me.

[–] andrei_chiffa 1 points 1 year ago

R-36 "Satan" was desinged by and manufactured at Yuzhmash, now Pivden'mash, located in Dnipro, Ukraine. More recently, Pivden'mash has been building "Zenit" rockets, that has >70 successful launches and has a 13.7 t payload to LEO.

I think Ukraine is mostly waiting for a proper excuse rather than capabilities to send non-nucler ICBM in towards strategic locations in Russia.

[–] andrei_chiffa 14 points 1 year ago (2 children)

A) We already don't know how neurons interconnect (eg why infants loose ~ 70% of their neuron connections between 1 and 3 years). B) That's not how dopanime works C) That's not how Parkinson works either

[–] andrei_chiffa 20 points 1 year ago (6 children)

I find it fascinating how few people remember the time when Greenpeace was literally selling Russian gas.

[–] andrei_chiffa 2 points 1 year ago

Russian strongmen culture does not tolerate well traitors.

Wagner mercs saw it first hand in prisons. Russian army saw it first had during the recruits mass-rape and torture nights.

Nobody is getting assimilated and they all know it.

[–] andrei_chiffa 22 points 1 year ago (2 children)

I don't think it's only a psyops.

One think is getting hit by drones and missiles. It's a whole different level to not spot a landing squad crossing almost 100km of sea, land and blow up your critical military installation.

They likely already did it last year, when they blew up planes on a Russian base in Crimea, but it is nice to see that they still very much can do it.

[–] andrei_chiffa 16 points 1 year ago (2 children)

Realistically, LTT needed a proper CEO some time around the time when they crossed the 20 employees threshold. Better late than never, but it might have been too late now.

[–] andrei_chiffa 2 points 1 year ago (1 children)

No, no - it's just as scientists predicted. In the worst-case "no-mitigation" scenario and with attempts from them to explain that +2 global will likely be +10 in peak temperature increase over land (read US, Europe, Asia). As in, both mean and std will increase, but without ocean's mitigation over land.

Fucked is not the correct word - there is a +50 predicted before the end of decade in Strasbourg, where I am from. There is not a single building built there made to resist that kind of temperatures, nor a single tree or crop that could stand that for a day.

And it's a relatively "safe" area as far as long-term projections go...

[–] andrei_chiffa 7 points 1 year ago

A lot of great companies were remote focused for a very long time before the pandemic. ArsTechnica, StackOverflow, ... - they have a physical office space, but it's mostly for legal & admin purposes and to let externals tour at least something.

[–] andrei_chiffa 6 points 1 year ago

That show is about as "over" as the war in Ukraine on Feb 26th 2022.

[–] andrei_chiffa 2 points 1 year ago

That's a weird way of saying "bombing their own cities"

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