I brought a hex key to adjust my seat and just went riding. Test, adjust, test, adjust.
Some of the things I've spent money on that has not done anything for my riding comfort is a seat dampener, so maybe skip that one if you were thinking about it.
There's also a break-in period for any setting, I've found. My ass used to hurt a lot after riding a bit but now it doesn't. Your body will adjust- the important thing is to make sure you're not riding in position that puts unnecessary stress on your spine or something.