this post was submitted on 01 May 2024
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This study describes the identification of an antibiotic class acting via LpxH, involved in lipopolysaccharide synthesis having potent in vivo efficacy against bloodstream infections caused by the critical Gram-negative pathogens E. coli and Klebsiella pneumoniae. Further development of this class of antibiotics could make an important contribution to the ongoing struggle against antibiotic resistance.

https://www.pnas.org/doi/10.1073/pnas.2317274121 (open access)

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[–] Plopp 2 points 6 months ago

Yes, this is SPARTA! Pour it on everything quickly or we might all die!!1!