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2024-11-11

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As Cancer Treatment Advances, Patients and Doctors Push Back Against Drugs' Harsh Side Effects (apnews.com)

submitted 9 months ago by cymbal_king to c/science

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For cancer patients, the harsh side effects of powerful drugs have long been the trade-off for living longer. Now, patients and doctors are questioning whether all that suffering is necessary.

They’ve ignited a movement to radically change how new cancer drugs are tested, with the U.S. Food and Drug Administration urging drugmakers to do a better job at finding the lowest effective dose, even if it takes more time.

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[–] Someology 6 points 9 months ago* (last edited 9 months ago)

I have a loved one with permanent nerve damage from chemo. We're very happy the chemo was successful, but imagine a combo of numbness and constant pain for the rest of your life in all your fingers, which becomes dramatically more severe with exposure to cold. It makes make simple daily life tasks from driving, to cooking, etc. far more difficult. They do not tell patients in advance they are going to continue the treatments until the point where permanent damage happens. You only realize after going through it that this was the plan all along. It makes medical talk about informed consent feel ridiculous. The severity fluctuates, but it has already been like 7 years, and this is never going away. It is not for "a while".