Witcher 3 is probably my favourite game of all time, largely because of the semi-parental storyline with Geralt, Yennefer, and Ciri. That said, I think the weakness with the Witcher 1-3 series as a whole is that the plot is too complex. Since most modern AAA RPGs have many, many side quests, I think the main plot of a long RPG should be relatively simple or else risk diluting its dramatic effect.

I feel like CD Projekt Red did a better job with that aspect of story-telling in Cyberpunk, even if the overall emotional arc is less intense than that of Witcher 3. There are lots of cool things to do and interesting side quests in Cyberpunk, but the main arc is pretty simple. You can go off on hours of side quests and still come back to the main plot without forgetting what's going on.