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No, because those mutations happen anyways. Mutations are random.
And the mutated versions would still spread the same.
Besides, viruses don't want to kill people, a dead host isn't a host anymore. If it kills too fast, it doesn't spread. So there's evolutionary pressure for a virus to not kill or even significantly harm it's host.
That's why viruses that killed a shit ton of people centuries ago are either not around anymore, or just a small nuisance.
Vaccines just speed that up so it takes months/years instead of decades/centuries
The mutations may still happen, but if they have to compete against those who don't have the mutation and lose, then they'll die out. So the question is whether this competition for resources happens or not.
COVID kind of threw this out the window, what with being highly contagious for several days prior to onset of symptoms. For most illnesses, it's usually what, 24 hours?