Not from that field, and I think it depends a lot of the field, country, etc, but research is not an idilic world at all and deal with huge flaws from the real world, institutions, society and economics, not aside of human being's flaws, so it can be deeply disappointing in some aspects. I believe is a natural in any guild (there is shit everywhere, e.g. police require internal affairs for a good reason, but not only, they suffer from funding restrictions, metrics for promotion, etc, and the same can be said for medicine, politics, etc) so in the end it may be your ability to deal with real world shit... and luck.