karce

Hey everyone. Hope everyone is having a good day and feeling positive about yourself!

I wanted to open a discussion about expectations that I (and many others maybe as well) set about results or experiences we're "supposed" to have from mushrooms and other psychedelics. I tend to trip a few times a year as a sort of therapy. I find that it helps me balance out my mood and improve my confidence significantly for a few months after a trip.

One of the things I still tend to struggle with when going in to a new trip is trying to temper my expectations for it. I don't want to put too much pressure on myself that this is going to work (or that it has to work) to help me stay in good health. I think this is why I try to downplay the effects for myself when I can so there is less pressure for the trip itself. Since I feel like additional stress and pressure will negatively affect the trip.

Does anyone else experience anything similar to this? How do you deal with it?

On another note, I find when I'm coming into a trip one of the first thoughts I always have is "Is this what its supposed to feel like"? Then I go down the rabbit hole of "What is 'supposed to' mean, anyway? Who is the one behind this 'supposed to'?" It is very strange but also predictable for me now. Like my mind always happens to go there first. Anyway, thought I would share. Happy Friday!

You may have noticed that emails haven't really been working on this instance properly if you've tried to reset password, for instance.

Just wanted to let folks know that they should be working properly now and to use it if they need it, for notifications or password reset or whatever else.

I ended up signing up for email hosting for a little while, which is still a free trial but should provide this functionality for us for a few months with zero cost.

I'm now going to start requiring email verification for new applications. I also get emailed when new people sign up too so I can be on it quickly and approve real people. Should be a good time overall.

Hope everyone is doing well! Just got off vacation myself but looking forward to watch our little community grow. Also happy 4th of July!

I turned on registration applications today since we had someone out there making tons of bot accounts on this instance.

Also since I don't have a ton of control over what these accounts are doing I'm just going to be banning and then deleting them between Jun 18 at 6pm EST to Jun 19 at 9pm EST.

New accounts that go through the registration should be good to go. Anyone who had an account before then should be good too. Let me know if you got caught up in it or are having issues. If you need to, make a new account.

Thanks everyone, I feel confident this is the best way to handle it so we don't have an artificially inflated number of 'users'

Psychedelics are a broad class of drugs defined by their ability to induce an altered state of consciousness. These drugs have been used for millennia in both spiritual and medicinal contexts, and a number of recent clinical successes have spurred a renewed interest in developing psychedelic therapies. Nevertheless, a unifying mechanism that can account for these shared phenomenological and therapeutic properties remains unknown. Here we demonstrate in mice that the ability to reopen the social reward learning critical period is a shared property across psychedelic drugs. Notably, the time course of critical period reopening is proportional to the duration of acute subjective effects reported in humans. Furthermore, the ability to reinstate social reward learning in adulthood is paralleled by metaplastic restoration of oxytocin-mediated long-term depression in the nucleus accumbens. Finally, identification of differentially expressed genes in the ‘open state’ versus the ‘closed state’ provides evidence that reorganization of the extracellular matrix is a common downstream mechanism underlying psychedelic drug-mediated critical period reopening. Together these results have important implications for the implementation of psychedelics in clinical practice, as well as the design of novel compounds for the treatment of neuropsychiatric disease.

It's webp at least : )

cross-posted from: https://lemmy.world/post/86663

Seriously, though, Comic Sans was originally designed to be legible at the smallest possible font size, and the lack of hard lines makes it easier to read!

This article is hilarious and I strangely like it.

cross-posted from: https://beehaw.org/post/526831

Great writing on the current Reddit saga. The author put down in words a lot of things in my mind I couldn't find the right words.

Thought this article was interesting so I'm cross-posting it here as well!

cross-posted from: https://wizanons.dev/post/996

Hey :) I'm writing this comment using "Jebora for lemmy" is there other apps for mobile browsing? which one would you recommend? (Android)

If anyone needs help with the website, or with lemmy in general! Ask me here! I can provide support and help out our fellow apprentices.

Website is brand new. Lemmy is fairly new and I've been learning a lot over the last couple weeks after the Reddit purge.

This is an awesome resource for everybody to know about and read for staying safe with an type of substance. Linking it here since it is so useful.