Take Dueling skill. Melee is effective, you save on bullets, and when you do need to shoot someone, you absolutely can.
I'm seriously thinking of doing a mainly physical build. Maximum hand-to-hand tanky-ness. (I'm thinking "File Not Found" and play her like River Tam in Firefly). It could be fun to spend the start of the game hunting and scavenging outside of New Atlantis.
I know what you mean about the price. I admit, I came within a hair's breadth of saying "sod it - I'll come back in a year and buy it discounted". Main reason I didn't was I didn't want to get the game spoiled any more than necessary ... and I felt like it was about time I paid full price for one of their games.
How many glitched NPCs have you seen, anyway? In 260 hours I reckon I've seen it about twice, Sarah both times. And there's been a couple of occasions where a companion has temporarily decided to stand at the doorway and sulk for some reason, and that's pretty much it.
What did annoy me was the bug where you sell a captured ship at the Den and get teleported back to New Atlantis with no ship exterior and no ground mesh in the spaceport. That was annoying, but I expect we'll see a fix for that sooner rather than later.