this post was submitted on 29 Jun 2023
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Aspartame is also linked in some studies to weight gain, GI disorders, mental health issues and more:

According to some studies, aspartame and other artificial sweeteners can lead to weight gain instead of weight loss 12. Aspartame has been linked to increased appetite, diabetes, metabolic derangement and obesity-related diseases 2.

One study showed that aspartame causes greater weight gain than a diet with the same calorie intake but no aspartame 1. Another study found that even acceptable daily intakes of aspartame might make you hungrier and lead to weight gain 3.

...some research suggests an association between aspartame intake and metabolic damage to the central nervous system (CNS), such as changes in enzyme and neurotransmitter activities 2. Aspartame acts as a chemical stressor by elevating plasma cortisol levels and causing the production of excess free radicals. High cortisol levels and excess free radicals may increase the brain’s vulnerability to oxidative stress which may have adverse effects on neurobehavioral health 3.

There is also some evidence that high-aspartame consumption may lead to weaker spatial orientation, irritability, depression, and other neurobehavioral conditions 14. However, these studies are limited in scope and further research is needed to determine the long-term effects of aspartame on human health.

Worth researching more, especially if you eat/drink anything with this stuff - and it's in a lot of food products.

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[–] [email protected] 6 points 2 years ago (3 children)

Is this going to be like pork where it's a ~20% increase in cancer or like smoking where it's like a super huge increase?

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[–] Crow 6 points 2 years ago (1 children)

Luckily I find the taste of aspartame very off-putting. Please don’t take my sucralose.

[–] Bazoogle 3 points 2 years ago (1 children)

Interesting. I can hardly distinguish aspartame and sucralose. Both taste disgusting. Give me my diabetes inducing high fructose corn syrup please.

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[–] [email protected] 6 points 2 years ago (2 children)

Looks over at his Sweet N Low packets 😬

(I know, saccharin vs aspartame)

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[–] JesusTheCarpenter 6 points 2 years ago (1 children)

I am curious whether this will actually impact what is considered safe to consume on a daily basis.

Again, many things are unhealthy and carcinogenic in large quantities. The infamos study showed that Aspartame was causing cancer in mice but the amounts they were given would be like humans eating bags of it every day.

[–] ilex 5 points 2 years ago

Is aspartame regulated?

The FDA ... sets an acceptable daily intake (ADI) for [Aspartame], which is the maximum amount considered safe to consume each day during a person's lifetime. [EFSA is the Euro version.]

The FDA has set the ADI for aspartame at 50 milligrams per kilogram of body weight per day. [EFSA's is 40mg/kg]

FDA estimates that if all of the added sugar in the diet of an average 60 kg (132 lb) person were replaced by aspartame, it would result in an exposure of about 8 to 9 mg/kg/day.

In order to reach the ADI of 40 mg/kg/day, an adult weighing 60 kg (132 lb) would have to drink 12 cans of a diet soft drink (if it contained aspartame at the maximum permitted levels of use), every day. [Goes on to say in practice it would be 36 cans, because reasons]

[–] aragon 6 points 2 years ago (2 children)

There are so many artificial sweetners in the market now.Even purely natural onea like stevia powders have maltitol added to it. It might be better to give up sweet things completely may be with the exception of fruits for better health.

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[–] [email protected] 4 points 2 years ago

This is basically the case for every artificial sweetener lol

[–] darthfabulous42069 4 points 2 years ago

Stevia and monk fruit taste better anyway

[–] scarabic 4 points 2 years ago

I’m more interested to keep seeing research on stevia and monkfruit extract.

[–] [email protected] 4 points 2 years ago (1 children)

I'm not sure because I think more studies need to be done.

What I do know is I never liked diet coke or anything with artificial sweeteners. Never drank them. But when I got cancer I craved it. During chemo it was the only thing I could drink without issue. So there's that.

[–] [email protected] 4 points 2 years ago* (last edited 2 years ago) (1 children)

I hope you're doing well.
I was looking for more information on this topic and browsing this Study suggests association between consuming artificial sweeteners and increased cancer risk and chuckled seeing this in the section describing limitations:

reverse causality cannot be ruled out

Which I guess means the participants that had cancer later means the (undetected at time of study?) cancer made them consume more Aspartame? Sort of fit your anecdote.

[–] [email protected] 3 points 2 years ago

Thanks, I'm doing great. I won officially in January. Now it just maintenance and scans a few times a year.

That's an interesting study. Thanks for sharing. Now I feel less crazy about it, lol.

[–] BlueN1te 3 points 2 years ago

In other news, blood Is red. Jk. In all seriousness we have known aspartame causes issues for awhile now

[–] _kato 3 points 2 years ago (1 children)

I'm so glad I was finally able to give up soda, not because of health reasons but I just started disliking carbonated beverages. With findings such as the amount of sugar they contain as well as the aspartame study I'm probably never looking back.

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[–] yolk 2 points 2 years ago

Hasn’t this been known for a while? It’s still really tasty tho lol

[–] [email protected] 2 points 2 years ago (1 children)

Hasn’t it already been proven to facilitate the development of Alzheimer? Honest question - I’m a layman in medicine and just worried about my dad chugging tons of diet products full of aspartame, thinking it’s the healthy choice (as opposed to non-diet lemonade for instance).

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