Therapeutic Ketamine

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Discussion of prescription ketamine for pain and mental health indications.

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Comparative efficacy of racemic ketamine and esketamine for depression: A systematic review and meta-analysis (Bahji, et al, 2021) (psycnet.apa.org)

submitted 1 year ago by PlanetMedicines to c/therapeutic_ketamine

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24 trials representing 1877 participants were pooled. Racemic ketamine relative to esketamine demonstrated greater overall response (RR = 3.01 vs. RR = 1.38) and remission rates (RR = 3.70 vs. RR = 1.47), as well as lower dropouts (RR = 0.76 vs. RR = 1.37). Conclusions: Intravenous ketamine appears to be more efficacious than intranasal esketamine for the treatment of depression. >

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