Zepbound, Weygovy, Mounjaro and other GLP-1 medications

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Discussions about weight loss, challenges and victories (on the scale and otherwise) using GLP-1 medications.

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DelightfullyDivisive

Increase in DOMS? (self.zepbound)

submitted 9 months ago by DelightfullyDivisive to c/zepbound

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Another of my posts from Reddit in recent weeks:

Does anyone else experience an increase in DOMS (delayed-onset muscle soreness) after starting zepbound? I have ramped up the intensity of my workouts lately, and it seems like muscle soreness has gotten much worse.

I'm thinking I should dial it back a bit, because it is also stimulating quite a bit of appetite. Not really what I want when I'm trying to cut calories and weight. 🤔

Addendum: The consensus was that a lot of people experienced more difficulty completing endurance workouts, but not specifically weight training (which is where DOMS usually comes from).

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[–] PlantJam 2 points 9 months ago

I agree with your conclusion to dial it back a bit. Either more rest, less intensity, or both.