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Pfizer says it will price Covid treatment Paxlovid at nearly $1,400 for a five-day course, which researchers estimate only costs Pfizer $13 to produce. That's a 10,000%+ markup. Shameful. (mastodon.world)

submitted 1 year ago by i_have_no_enemies to c/technology

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[–] [email protected] 149 points 1 year ago* (last edited 1 year ago) (38 children)

While I'm sure there is a crazy markup, it's important to note the cost to produce - as in manufacture - does not include the cost of drug discovery, which is extremely expensive and involves a good amount of risk over a long period of time.

You can't just compare the cost of discovering a new drug vs. cost of producing a generic without any research like that.

[–] [email protected] 139 points 1 year ago (5 children)

https://jacobin.com/2023/09/big-pharma-research-and-development-new-drugs-buybacks-biden-medicare-negotiation

Last year, the three largest US-listed pharmaceutical companies by revenues, Pfizer, Johnson & Johnson, and Merck, spent a combined $39.6 billion on R&D. That is, admittedly, a lot of money. But less than Medicare is currently paying on just ten drugs

While Big Pharma holds vast portfolios of existing patents for prescription drugs, the innovation pipeline for new drugs actually has very little to do with Big Pharma. In reality, public sources — especially the NIH — fund the basic research that makes scientific breakthroughs. Then small, boutique biotech and pharmaceutical firms take that publicly generated knowledge and do the final stages of research, like running clinical trials, that get the drugs to market. The share of small companies in the supply of new drugs is huge, and it’s still growing. Fully two-thirds of new drugs now come from these small companies, up from one-third twenty years ago. It is not the research labs of Pfizer that are developing new drugs.

[–] repungnant_canary 14 points 1 year ago (2 children)

I like Lemmy for exactly this - whenever someone incorrect makes a statement they're factchecked.

Thank you kind person for finding and sharing that source.

[–] flawedFraction 43 points 1 year ago (1 children)

OP didn't make an incorrect statement though. What they stated was an important part of the equation. I think a lot of people don't take that type of thing into account and they will read what this post says and assume that Pfizer should be charging $13, or maybe something pretty close like 15 or 20. Clearly 1400 is far far too high, 13 is too low. A reasonable price allows the manufacturer to be successful while not gouging consumers lies somewhere in between, but much much closer to the low end than the high. To me that's really what the person you are responding to is giving evidence for.

[–] [email protected] 11 points 1 year ago

Thank you, this is exactly my point.

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