this post was submitted on 14 Jun 2023
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Biology

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[โ€“] J23 12 points 2 years ago (1 children)

I wonder what they actually did. My naive impression is that they kind of took the intersection of a collection of genomes. But how do you validate the choice of genomes, and show such an organism existed?

[โ€“] [email protected] 6 points 2 years ago

I'm not sure about this particular paper, but usually you can compare the number of mutations in a common protein and use that to estimate how long ago a common ancestor existed. As an example here is a graph of the number of mutations in mitochondrial DNA for the protein Cytochrome C. The more mutations you accumulate in a genome the larger amount of time since they split from a common ancestor.

Neutral Mutations in Cytochrome C