Mental Health

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Do you think SSRIs are a good idea? (self.mentalhealth)

submitted 2 months ago* (last edited 2 months ago) by Psychonometry to c/mentalhealth

NSFW 25 comments fedilink hide all child comments

Mild NSFW warning: this post mentions sexual side effects of medication.

SSRIs are the most common type of antidepressant (examples are Prozac/fluoxetine, Zoloft/sertraline, Paxil/paroxetine).

If you have experience with them, do you think they're a good idea?

I came across a paper about side effects which I haven't heard discussed before. Many people know that SSRIs have sexual effects, but apparently they also affect fertility.

This paper describes SSRIs as "gonadotoxic", leading to effects like "decreased sperm concentration and motility, increased [DNA] fragmentation, and decreased reproductive organ weights".

The paper does say "this effect does seem to be reversible", so if you stop SSRIs, your sex organs should apparently go back to normal. But still, some people are on SSRIs for long periods of time, right?

I would be interested to hear others' thoughts, if you have any.

Edit: Thanks for the replies to this post, they're interesting.

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[–] rowinxavier 2 points 2 months ago

I would second this. My partner was on an anticonvulsant for a bipolar diagnosis. Why? Because it is used, at a lower dose, as a mood stabiliser. She had limited effect at the sstandard dosage, so the psychiatrist went up in dose to get an effect.

Ultimately she got off all of the meds and is doing better without them, but that is her and her experience, the meds may be useful for some people and not others.