I honestly doubt that. The average user doesn't care about this, they probably don't even know what "sideloading" means.
I'm also not gonna go out and buy an iPhone just because sideloading is an option now. Not saying no one will, it just won't be enough to matter.
This and the fact that we're talking about nicotine here, not cigarettes directly.
Inhaling vapor is much less unhealthy (still unhealthy) than inhaling cigarette smoke.
And what about nicotine patches? Should we can those because people don't like inhaling smoke? Doesn't make sense.