DRx

So, as a pharmacist, I can tell you that Tetracyclines (class of drug which includes Doxy, Minocycline, Tetracycline) have been used as prophylactic drugs for quite a long time, and not just for their anti-microbial activity.

Minocycline for example is used prophylactically for recurrent UTIs, suspected meningitis, and frequent SSSI by staph

Doxycycline has been used long term for Acne prevention, Malaria prophylaxis, and STI treatment and prophylaxis.

While I do worry about overuse of Antibiotics in general. It seems that tetracyclines as a class have been used quite frequently over the last 50+ years. I am sure that in small pockets of the LGBT+ populations (the scope of this indication, it seems) you may see some resistance that will need to be treated with other antibiotics, but I don't think that we will see much cross-over into the general public. Furthermore, it looks like their is a new class making its way to hospitals soon that can get around the resistance seen, but we will need more studies to further nail that down.

KCl labeled as asa? As a critical cardiac care nurse, I am duly horrified.

Trust me, so are we. Typically, the reason for the mislabel is due to the machine that is used for pre-packing from stock bottles. For the most case, standard meds are given their own containers for the machine, but when there was a KCL shortage going around something happened where a standard container was used for a non-standard medication and they didn't make sure the old container was cleared before adding the new medication.

That being said the pyxis pharmacist checking, should have looked at EVERY pre-packed med (100 per batch typically) and see that they all looked correct (eg: no doubles, empties), and would've seen the size mismatch between the 2 meds lol. We have some great techs though and one of them caught it as they were doing their pyxis load.

Love my crit care nurses though! We have 5 ICUs (+ ER/Trauma) and most all those nurses typically have their stuff together, which makes my job much easier, when I gotta call with questions! So, thank you for being on the ball!

75-80% of the time. All the staff I work with will take initiative at some point, but some do it more/better than others. I have a certain level of trust with some co-workers that I do not with others.

As an example, We have 15ish pharmacists on staff (non-admin) and 25-30 techs... There are probably 5 or 6 pharmacists and 1/3 of the techs, that when I come in (rotating schedule btw) and I see "those people" are working I know I need to buckle down and really scrutinize what is going on.

Now, like I said in the first post, everyone makes mistakes. Including myself. But I think there is a difference between the mistakes and how they are handled.

There is this mentality of "I didn't do it, So it isn't my problem". When really we should be looking at it as an "institution problem", or its everyone's problem! For example, the other day a doc called about starting a bicarb drip on a Hyperglycemia patient. We have a policy on hand to do 150 bicarb in 1L Sterile water. However, this one pharmacist doesn't like using sterile water (because of HYPOtonic concerns), so instead talks the doc into doing a 150 bicarb in 1/2NS (well this makes it a HYPERtonic soln now and the patient only has a peripheral port AND their sodium is already 141)... OK well when it got to the IV pharmacist, they shouldve said WOAH what it going on here! Instead they let it through because another pharmacist did the order and it isn't theyre problem if something goes awry. I would have called out there and said WTH are we doing? this isn't policy! and got it changed.

In the grand scheme, the ordering pharmacist did talk to the phsycian and got the okay, but in the real world physicians are not as infallible as they are portrayed, and our pharmacist gave an inappropriate option for treatment, which the physician trusted was an okay treatment plan. Was the patient injured by a single infusion? no. However, it was a continuous infusion and when I saw the nurse was asking for a refill to start the 2nd dose, I said WTF is going on here and started digging.

Let me say though that this is a national problem, not just my hospital. Also, the things that usually go through when they shouldn't is stupid things that never effect the patient. When it comes to dangerous medications, we have different procedures for checking of orders, or it goes through a specialist pharmacist first (eg: chemo pharmacist, pediatric pharmacist, critical care, infectious disease, etc you get the point). It is more of an annoyance on my part because I usually take the time to fix a problem when I see it, and other will let stuff slide because theyre not the ones who'll get the variance, and it won't hurt the patient anyways.

Just for posterity sakes, if you are curious, what is a "mistake that doesn't effect the patient"?

Example: We have a NICU and those little babies will be put on continuous infusions sometimes like dopamine to improve their cardiac functioning. So, all our NICU orders are standardized to the weight of the baby to determine the size of the order. So let's say that the order calls for 0.06ml/hr. That is 1.44ml/24 hr period. So, we would most likely send a 3ml syringe (to allow for titration). Well when the order is sent electronically to the pharmacy it always come stock as 1ml, and we have to change it to the appropriate size. If it isn't then the nurse will be calling for refills more often than needed based on titration (1ml = 16.6 hour infusion). This is a mistake that is counted towards us.

Is it teachable? sure, pharmacy school rammed it down our throats. However, being short staffed makes people cut corners, and that become the learned state in those situations.

Ya know a lot of ppl think pharmacists are just about putting pills in a bottle… but in all honesty in the role that I work clinically in a trauma center, I would say what sets a good pharmacist from a mediocre one is being able to catch everyone’s mistakes.

Your fellow pharmacists, techs in the pharmacy make mistakes (150 bicarb in 1/2NS?? lol) (incorrect pre packing procedures and getting kcl w an asa label)

Your docs make mistakes (2000mg q12 vanc on an esrd pt with a bmi of 45 + Zosyn 4.5 q6)

Your nurses make mistakes (y-site compatibility, missing doses, losing meds, etc)

The issue is noticing the problem and taking initiative to fix it. Unfortunately, either by ignorance, not correctly verifying, or just plain laziness can lead to sub optimal care for our patients.

It’s not easy though. I easily go through 500-1000+ orders a day, while calling doc/nurses, double checking techs and other pharmacists work. It can be stressful, and it’s easy to put blinders on and just keep hitting approve, but the pharmacists who look at that 4th 40meq kcl bag of the day for 1 patient without a lab drawn in 18 hours and calls the provider to see if maybe they want to draw a lab before the next admin. Those are the pharmacists doing a good job. This can go for the retail folks too who have to put up with way more shit than I.

Not worried in the least, house is < 10 yo and don’t plan on moving anytime soon. I also think my houses “value” is over inflated anyways.

Now if I bought in the last 3 years? Yea I might be sweating a little bit about being under water, depending on price and location.

Nice! I had it on my list, but hadn't seen salo yet, thanks for the reminder!

A Serbian film... That ending I just cant... It is the only movie I actively tell people to avoid. My wife and I like to watch the most mind-fuck movies imaginable, but that one took it a step too far. We literally just stared at the screen for like 5 min after it was over.

So unless you live in an area with fiber, asymmetrical speeds are pretty typical… I’m not sure if it is because it’s all coax so there are infrastructure limitations? But it’s actually gotten faster because 6 months ago my upload was only 30 mbit/s.

Once fiber is in my area I’ll switch to that, but symmetrical will add more cost…but of course it will lol

Since the day before the Reddit strike… so mid June?

So... I see a lot of talk about "security", but no specifics about HOW this is more secure than searx or searxng (which I use).

What specifically is insecure with searx or xng? and what makes Websurfx MORE secure? Does SearX/NG have memory or other security flaws you can point to? (Ive been searching and can't find anything specific, unless your self-host is insecure, but that on the user not SearX/NG)

It is my understanding that searx and xng are very privacy focused as when you search it send individualized tokens each time, so it is as if a fresh browser with no previous queries is being used. This is so an ad profile cant be built around you. It is also fully customizable, and in my opinion plenty fast.

I am just playing devils advocate here, I am sure your search engine is fine; however, I just see red flags when someone says "Hey we are better" but then doesn't explain why. Generic words like "Privacy, Security, and Speed." multiple times in the write up needs to be expanded upon IMHO.

"Is God willing to prevent evil, but not able? Then he is not omnipotent. Is he able, but not willing? Then he is malevolent. Is he both able and willing? Then from whence comes evil?"

-Epicurus

O-State 4th qtr and end game

O:

• OLLIE!!! what a man! Steppin on toes and breaken ppls nose
• Finally another TD!!! we got some chunk plays that drive and gunnar was great.
• TD #2 of the qtr ... OLLIE!!! OK BOYS WE ROLLING NOW!!!

I am cautiously optimistic about our Offence... The weapons are there, but they need the reps... The biggest issue (like every year) will our O-line hold up?

SP:

• Another FG block!!! lets GOOOOO (PAT block)

VERY happy with SP teams today. Picking up where we do every year. Gundy is our Sp Teams coach, so I expect them to play well.

D:

• Stepped up the plate when it mattered the most, and got some stops
• 5 sacks makes me happy
• Going forward, I am still pretty worried about our D. They need a lot of work if we are going to win the minimum.

Ill say this, Im happy for the win, but I am a realist. 6 wins and a bowl and Im happy. 8 or 9 wins (including the bowl) and Ill be VERY happy for this season. We have a lot of potential, but with 51 new players this year, I cant see that we will be good enough fast enough. Gundy has surprised me before, but like I said... I am a realist.

VICTORY!