Bebo

joined 10 months ago
[–] [email protected] 5 points 1 month ago

The Left Hand of Darkness. That's her first scifi book I read and fell in love with it. I will add here the review I wrote when I read it:

In this book Genly Ai is sent to the planet Gethen on behalf of the Ekumen, an alliance of human societies residing on far flung planets, to acquaint the inhabitants with the existence of the Ekumen and convince them to join the alliance. The Gethenians are unique: every individual has the potential to be a man or a woman during regular periods of time, referred to as "kemmer". The period of kemmer is the only time when a Gethenian has a defined sexuality. Throughout the course of the book any individual Gethenian is referred to as a "man". The narrative is told through two POVs, both in the first person: Genly Ai, the Envoy; and Estraven, who is the prime minister of Karhide, Mr Ai's liaison with the nation's king. Over the course of the narrative, Le Guin explores a society totally uninfluenced by sexuality which interestingly holds up a mirror to how sexuality /gender permeates every nook and cranny of our social existence. It was however the beautiful depiction of the progression of the relationship between Mr Ai and Estraven that made me fall in love with this book. The complete disconnect between the cultures of the two main characters initially made them misjudge each other leading to dangerous consequences. Later, unexpectedly thrown in together while traveling for days in the icy wilderness, they begin to understand and accept each other for who they are; the story ultimately culminating into it's heartbreaking conclusion. I will end with these beautiful lines: "Light is the left hand of darkness and darkness the right hand of light. Two are one, life and death, lying together like lovers in kemmer, like hands joined together, like the end and the way."

[–] [email protected] 2 points 1 month ago

Read. Study topics I don’t know about. Learn new skills and try out new experiences. Travel to different places I haven't visited before.

 

From forming bound states to normal scattering, many possibilities abound for matter-antimatter interactions. So why do they annihilate? There’s a quantum reason we simply can’t avoid.

 

Clinical relevance of miRNAs as biomarkers is growing due to their stability and detection in biofluids. This study has identified miR-519a-3p as a potential early biomarker for Alzheimer’s, linked to prion protein expression. This molecule is directly associated with the expression of the cellular prion protein located on the surface of nerve cells. miR-519a-3p may potentially be used as a biomarker of preclinical stages of the disease.

https://www.sciencedirect.com/science/article/pii/S0925443924001765?via%3Dihub (open access)

[–] [email protected] 2 points 1 month ago

That's for sure!

 

The article referenced:

https://iopscience.iop.org/article/10.3847/1538-3881/ad34d5 (open access)

[–] [email protected] 2 points 1 month ago (2 children)

Oh this is partly how listening to music works for me. I'll be listening to some particular songs in the moment repeatedly, get fed up of either all of them at once or one by one, then just stop listening to those that I get fed up of. I'll then again listen to music when I again feel like listening to some particular music.

This is not directly related, but one reason I stop myself from binge watching TV shows is that if I end up watching too many episodes of a TV series at one go it can end up ruining the show for me, regardless of how great it may be, because watching too many episodes at one go makes me so fed up of the show that I don’t feel like watching it anymore. Binge watching almost ruined Breaking Bad for me; since then I make it a point to never watch more than 2 episodes of a show in a day. I generally restrict myself to one episode per day.

 

The perception of taste is remarkably complex, not only on the tongue but in organs throughout the body.

The idea that specific tastes are confined to certain areas of the tongue is a myth that “persists in the collective consciousness despite decades of research debunking it.” Also wrong: the notion that taste is limited to the mouth.

https://www.nejm.org/doi/pdf/10.1056/NEJMra2304578

[–] [email protected] 4 points 1 month ago

Thanks for sharing

[–] [email protected] 1 points 1 month ago

Love the smell of n-hexane and pet ether (worked in a chemistry lab). Though don't like the smell of gasoline. I kind of also like the smell of chlorinated water. Also chloroform, though not as much as n-hexane.

 

This study focuses on the manipulation of the plexin-B1 protein to enhance the brain’s ability to clear amyloid plaques in Alzheimer’s disease, opening avenues for future therapeutic strategies to potentially halt the progression of the disease

https://www.nature.com/articles/s41593-024-01664-w

[–] [email protected] 4 points 1 month ago

Doing a reread of Equal Rites, Children of Hurin and listening to Jane Eyre.

[–] [email protected] 1 points 1 month ago

Kind of had the same thought!

[–] [email protected] 2 points 1 month ago

ACC is mainly studied for its role in cognition and emotion. In the article linked it's mentioned >The ACC is one of the higher-order cortical regions that have been extensively studied for cognitive and emotional brain functions, but have been understudied for brain disease-related sensory abnormalities.> I also found another article on the role of ACC in cognition and emotion: https://neuro.psychiatryonline.org/doi/full/10.1176/jnp.23.2.jnp121

Also you can go through the Wikipedia article: https://en.m.wikipedia.org/wiki/Anterior_cingulate_cortex

[–] [email protected] 2 points 1 month ago

Oh yeah one of my favourite shows.

[–] [email protected] 3 points 2 months ago

In my case I've found the need to use Google for local searches, and certain very specific searches (one example is journal impact factors). In a lot of other cases, DDG has actually given me better results - I was getting fed up with some of the crappy results I was getting using Google, which prompted me to try out and eventually shift to DDG.

 

This study has identified the anterior cingulate cortex (ACC) as a key area in the brain responsible for sensory hypersensitivity in autism spectrum disorders. Utilizing a mouse model with a Grin2b gene mutation, heightened neural activity and connectivity in the ACC was observed. Suppressing this hyperactivity normalized the sensory hypersensitivity, offering new insights into treatment options

https://www.nature.com/articles/s41380-024-02572-y (open access)

[–] [email protected] 9 points 2 months ago (2 children)

Mostly using DDG now for sometime. Once in a while need to use Google.

305
Newton and Pascal (literature.cafe)
 
 

Really enjoyed this one.

 

Brain-machine interfaces implanted in the participants of this study in the supramarginal gyrus (SMG) and primary somatosensory cortex (S1) were successfully able to decode both internally spoken and vocalized words.

https://www.nature.com/articles/s41562-024-01867-y?utm_source=Live+Audience&utm_campaign=1586f44658-nature-briefing-daily-20240514&utm_medium=email&utm_term=0_b27a691814-1586f44658-52006460 (open access)

 

This study performed lineage tracing of live human embryos from the first cleavage division until the blastocyst stage and discovered that the majority of cells in the EPI, the future human body, originate from one of the two cells in most embryos. The first blastomere to divide at the 2-cell stage has a higher likelihood to generate the first, and more, internalized cells at the 8-to-16-cell stage.

https://www.cell.com/cell/fulltext/S0092-8674(24)00455-0?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867424004550%3Fshowall%3Dtrue (open access)

 

An interesting article on the time line of the universe.

The Universe passed through many epochs, from free quarks and gluons to stable protons and neutrons to neutral atoms to stars, galaxies, planets, and more. The precise time at which these various epochs occurred, including the (current) dark energy-dominated era, can be pinpointed with precision. Here’s how we know.

 

A cohort study found that individuals who engaged in mentally stimulating jobs during their 30s to 60s were less likely to develop mild cognitive impairment (MCI) and dementia after turning 70, highlighting the importance of cognitive stimulation during midlife for maintaining cognitive function in old age. [It is important to note that this study identifies associations rather than direct causation of dementia.]

https://www.neurology.org/doi/10.1212/WNL.0000000000209353

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