this post was submitted on 15 Dec 2023
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Danger Dust

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Pathogenesis of anti-neutrophil cytoplasmic antibody-associated vasculitis (www.ncbi.nlm.nih.gov)
submitted 1 year ago by Bampot to c/dangerdust
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One of the most commonly reported substances associated with the occurrence of AAV is silica.

The role of silica is further supported by the increasing frequency of AAV observed following 3 large earthquakes in Asia.

Silica-induced apoptosis of macrophages and polymorphonuclear leukocytes might act as a trigger of AAV, notably MPO-ANCA-positive MPA.

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