This library and command-line utility helps create SQLite databases from an existing collection of data.
Most of the functionality is available as either a Python API or through the sqlite-utils command-line tool.
sqlite-utils is not intended to be a full ORM: the focus is utility helpers to make creating the initial database and populating it with data as productive as possible.
It is designed as a useful complement to Datasette.
Cleaning data with sqlite-utils and Datasette provides a tutorial introduction (and accompanying ten minute video) about using this tool.