Danger Dust

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Bampot

Immune pathways can prevent lung healing after viral infection, study shows (medicalxpress.com)

submitted 3 months ago by Bampot to c/dangerdust

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The COVID-19 pandemic revealed how viral infections can cause long-lasting effects—a condition called long COVID. Also known as post-acute sequelae of SARS-CoV-2, long COVID has left a devastating trail of people who continue to live with long-term debilitation after infection. One such manifestation is scarring of the lungs—a condition known as post-acute sequelae of SARS-CoV-2 pulmonary fibrosis.

Those with long COVID can present with a broad constellation of symptoms, including post-acute sequelae of SARS-CoV-2 pulmonary fibrosis, which can cause severe difficulty breathing that requires oxygen supplementation. Patients with the most severe breathing difficulty may also need a lung transplant. Without additional treatment options, many patients are often left with long-term disability and life-threatening complications.

An aberrant immune–epithelial progenitor niche drives viral lung sequelae

https://www.nature.com/articles/s41586-024-07926-8

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