I'm not a fan of their approach to explaining it, but if you look at 08:50, you'll see that the Laplacian² is just the sum of second derivatives in each of your dimensions: f''(x) + f''(y) + f''(z).
I couldn't stomach watching the whole video, so I don't know how they define , and the parametrisation of x_0 representing a sphere on curve seems to become needlessly abstract for the topic of the video.