Warhammer 40K

I think often the RPGs can be better at the Satirical angle than the central wargame. Dark Heresy does encourage DMs to explore the themes — although the mechanics are a bit all over the place as far as supporting that goes.

Necromunda seems to be the one sub-property that actually tries to execute on the satire regularly and with any success, although it's not particularly focused. Don't know why, but I suspect having more Dredd\2000AD in its memetics helps.