This was a commission of a piece of rough I was asked to purchase at the Tucson Gem and Mineral Show a few years back. I cut it using a design by Arya Akhavan called Aperture Science.
There are a plethora of designs that can be found online and cut. The two sites I look through for ideas:
Take a look through those databases, and I'm sure you'll see some really interesting ideas/designs.
I believe she had it set in a pendant with surrounded by some tiny diamonds. I just supplied the stone, she went to her jeweler to have it set.