this post was submitted on 26 Jul 2023
62 points (94.3% liked)
Asklemmy
44151 readers
2342 users here now
A loosely moderated place to ask open-ended questions
Search asklemmy ๐
If your post meets the following criteria, it's welcome here!
- Open-ended question
- Not offensive: at this point, we do not have the bandwidth to moderate overtly political discussions. Assume best intent and be excellent to each other.
- Not regarding using or support for Lemmy: context, see the list of support communities and tools for finding communities below
- Not ad nauseam inducing: please make sure it is a question that would be new to most members
- An actual topic of discussion
Looking for support?
Looking for a community?
- Lemmyverse: community search
- sub.rehab: maps old subreddits to fediverse options, marks official as such
- [email protected]: a community for finding communities
~Icon~ ~by~ ~@Double_[email protected]~
founded 5 years ago
MODERATORS
you are viewing a single comment's thread
view the rest of the comments
view the rest of the comments
I'm having trouble finding it, but I ran across a study a few months ago whose results pointed to greater pain relief gains when CBD was consumed with THC, and that both substances alone do less to "relieve" pain.
I wouldn't say it helps relieve pain as much as it lets you be distracted from pain.
Also, personally, when I have used CBD on it's own, it never did anything for me at all. It only ever worked in combination with THC.
Finally, people taking other medications need to be careful about taking CBD.
The vast majority of medications are broken down by enzyme CYP3A4, an enzyme that CBD inhibits.
I am taking a life-saving/life-altering medication to manage a severe disease. It is handled in my body by CYP3A4. Meaning I can really fuck up my medication dosage by taking CBD on its own, because it will inhibit the ability of CYP3A4 to ingest the drug.
User [email protected] helpfully pointed out that grapefruit inhibits CYP3A4 as well, so if you're not supposed to eat grapefruit, you should probably also avoid CBD. I hadn't even made that connection myself, very astute, pizza_rolls!
Thank you for pointing that out! ~~In~~ I'm in the happy place of not having to take anything else on a regular basis, but it sure makes sense to keep the heads up of required.
Absolutely. I am glad I did the research myself and stumbled across this fact, because when I was prescribed this drug I bought a lot of CBD chocolates, thinking they would help. I was surprised that sooooooooo many prescribed medications use CYP3A4 as a pathway to enter the body, and how this isn't discussed more often. I really haven't seen very much discussion at all about how CBD can inhibit the effectiveness of a whole host of prescription drugs.
Anyway, cheers, glad to be sharing the info!
That is good to know. Guess I gotta research how my meds work
I used to take CBD every day for anxiety and I only found this out after a couple years so thanks for bringing it up. If your medication says to avoid grapefruit, then you probably should not take CBD
I didn't even make that connection, but yeah, exactly! Grapefruit inhibits the exact same enzyme. That's a really good way to know, I'm going to add that to my post.