Mental Health

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Do you think SSRIs are a good idea? (self.mentalhealth)

submitted 1 month ago* (last edited 1 month ago) by Psychonometry to c/mentalhealth

NSFW 28 comments fedilink hide all child comments

Mild NSFW warning: this post mentions sexual side effects of medication.

SSRIs are the most common type of antidepressant (examples are Prozac/fluoxetine, Zoloft/sertraline, Paxil/paroxetine).

If you have experience with them, do you think they're a good idea?

I came across a paper about side effects which I haven't heard discussed before. Many people know that SSRIs have sexual effects, but apparently they also affect fertility.

This paper describes SSRIs as "gonadotoxic", leading to effects like "decreased sperm concentration and motility, increased [DNA] fragmentation, and decreased reproductive organ weights".

The paper does say "this effect does seem to be reversible", so if you stop SSRIs, your sex organs should apparently go back to normal. But still, some people are on SSRIs for long periods of time, right?

I would be interested to hear others' thoughts, if you have any.

Edit: Thanks for the replies to this post, they're interesting.

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[–] Boinkage 3 points 1 month ago* (last edited 1 month ago)

Coupled with an excellent therapist, literally saved my life when I was struggling with depression. And my fertility has not been too hampered, if you know what I mean. It can surely have bad side effects for some people, but for others it is life-changing.