this post was submitted on 14 Sep 2023
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Seems that trials are already happening. As a person living with UC, this could be a game changer.

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[–] [email protected] 22 points 1 year ago (1 children)

Sounds too good to be true. Let's hope it's real.

[–] paddirn 8 points 1 year ago (1 children)

I’m sure it will be, just in time for some global apocalypse to render it a moot point.

[–] Sunstream 1 points 1 year ago

In fairness, I'd rather deal with an apocalypse whilst not living with pemphigus, so if I remain incredibly fortunate, I'd love to give it a go if it passes phase IVs

[–] Weslee 14 points 1 year ago (1 children)

Is there any tldr of which diseases this helps with?

[–] [email protected] 34 points 1 year ago (2 children)

TLDR would be that any autoimmune disease could see this helping. It “removes/erases” the white blood cells memory of the bodily molecule that we don’t want destroyed from their list of things to destroy.

[–] [email protected] 20 points 1 year ago (1 children)

That's incredible, and revolutionary if it works. I wonder if allergies will ever be treated in this way aswell

[–] [email protected] 3 points 1 year ago

With my beginner understanding of the immune response, they could if this is successful. Since allergies are the immune response to an external stimuli instead of an internal stimuli like an autoimmune disorder.

[–] Weslee 1 points 1 year ago

Thank you! That sounds like amazing progress, between this and CRISPR's progress with cancer, the future looks good for anyone suffering from these

[–] MossBear 10 points 1 year ago

Too late for me, but good news for those who come after.

[–] [email protected] 7 points 1 year ago (1 children)

God dammit, after I have my colon removed.

[–] MossBear 6 points 1 year ago

You and me both friend.

[–] SilenceInTheVoid 4 points 1 year ago

If this works out it would be a game changer, though most likely also priced as such especially if it is a one hit solution for diseases such as MS as there is a lot of money being made out of the current medication, hopefully it doesn’t get buried.

[–] [email protected] 4 points 1 year ago

That sounds amazing. I hope it all works out

[–] Bashnagdul 3 points 1 year ago

This might even work with allergies then!

[–] [email protected] 2 points 1 year ago (1 children)

How does one keep up with developments on something like this?

[–] [email protected] 4 points 1 year ago

It’s be a bit premature to do that, if you’re interested as a patient or layperson. It will also be all over the news in five years or so if it works and they bring it to market.

However, it looks like you could make an alert for the company name (Anokion SA) if you’re interested.

Those trials are conducted by the pharmaceutical company Anokion SA, which helped fund the new work and which Hubbell cofounded and is a consultant, board member, and equity holder

[–] [email protected] 2 points 1 year ago

Icahn. Sounds like a silver bullet. Hope it's true.

[–] [email protected] 1 points 1 year ago

@baruchin The technology seems relatively simple and low-risk: tag a molecule with a specific sugar... I wonder if this is something biohackers can manage to do before clinical trials and Big Pharma approval. If so, sign me up! #biohacking

[–] [email protected] -3 points 1 year ago (1 children)
[–] deafboy 31 points 1 year ago (1 children)

Not tonight, Pinky...

phase I safety trials have already been carried out in people with celiac disease, an autoimmune disease that is associated with eating wheat, barley, and rye, and phase I safety trials are underway in multiple sclerosis.

I know, I know. Safety studies do not judge the effectiveness, but at least they've actually moved on from mice to humans this time.

[–] baruchin 4 points 1 year ago