Most Excellent Physics Community.

Yes

Two axioms of science. Science doesn't prove things it disproves things. The hypothesis the earth is flat is disproven by empirical evidence. But, the hypothesis that the earth is spherical could also conceivably be disproven. Then we would have to come up with a new theory to explain all observed phenomena. However, as time goes on and a theory not only predicts new phenomena, but continues to fail to be disproven. We then believe the theory is "true."

Quotes on "true" lead into the second axiom. Falsifiablity. There must be a set of circumstances in which a theory can be disproven. Example. The existence of god is a non scientific theory. In days of yore god explained many things like the tides, or lightening, but these have gone on to be explained through science. The god thesis "moves back" becoming what is known as "the god of the gaps". Because god then always lies in an unknowable space, they can not be disproven, are non falsifiable, and are therefore non scientific. (Disclaimer. I am making no assertion on the existence of god. I'm discussing the philosophy of science)

Now to your question. Is it possible that a real portal appeared in your friend's room. Yes. But it's nonfalsifiable as there is no way to test it. Science has nothing to say about it. As far as the collapse of the wavefunction goes, this is quantum mechanics, which deals with things that are very small. The liklihood you observe a macro scale manifestation of quantum mechanics in the form of a portal are more than astronomically small. They are hundreds of orders of magnitudes larger than the age of the universe.

Portals. Non scientific (as of now) but as soon as they can be tested you'll find plenty of interested scientists!